教育经历

1996.08 – 1999.07 华西医科大学药剂学专业💛，理学博士（导师：陆彬教授）

1993.08 – 1996.07 第二军医大学杏悦注册娱乐药剂学专业，医学硕士（导师：周全教授）

1988.08 – 1992.07 第二军医大学杏悦注册娱乐药学专业，理学学士

工作经历

2013.1 杏悦药剂学教研室，教授、博士生导师

2007.2 杏悦药剂学教研室，教授、博士生导师，副院长

2006.2 杏悦药剂学教研室，副教授

2001.12 杏悦药剂学教研室，副教授👩🏿‍🔬，硕士研究生导师🫲，教研室副主任、院长助理

2000.10 杏悦药剂学教研室🥱🧜🏼‍♀️，讲师

2000.03 – 2000.08        中国人民解放军第208医院药剂科👰‍♂️，主管药师

1999.07 – 2000.03        中国人民解放军军事医学科杏悦毒药药物研究所

1992.07 – 1993.08        中国人民解放军第208医院药剂科🧖🏿‍♀️，药师

社会任职

中国颗粒学会药物制剂与粒子设计专委会副主任委员

世界中联中药药剂委员会第三🙆、四届理事会副会长

中国药学会药剂专业委员会委员（2010-2023）

中国医药生物技术协会纳米生物技术委员会常务委员

国家食品药品监督管理局药品审评专家

执行副主编🏌🏽：Acta Pharmaceutica Sinica B

副主编：Chinese Chemical Letters🧖🏼🌦、Journal of Biomedical Nanotechnology (2019-2023)、Journal of Drug Delivery Science and Technology

编委: AAPS PharmSciTech、Acta Pharmaceutica Sinica B、Archives of Pharmacal Research、Asian Journal of Pharmaceutical Sciences、Current Drug Delivery🛏、Drug Delivery Letters🏌️🧰、Heliyon、International Journal of Pharmaceutics、Journal of Chinese Pharmaceutical Sciences、Journal of Drug Delivery Science and Technology、MedComm Biomaterials and Applications、Pharmaceutical Research、Pharmaceutics、Processes、《药学学报》、《中国医药工业杂志》、《药学进展》

客座编辑: Acta Pharmaceutica Sinica B、Advanced Drug Delivery Reviews、International Journal of Pharmaceutics、Pharmaceutical Research👩‍👩‍👧‍👧、Pharmaceutics

代表性论著

共发表SCI论文200余篇🛗，Google Scholar引用1万余次🧬。

1. Qiuyue Liu, Jiahui Zou, Zhongjian Chen*, Wei He*, Wei Wu*. Current research trends of nanomedicines. Acta Pharm Sin B 2023, 13(11):4391-4416.

2. Yifan Cai, Xin Ji, Yunsen Zhang, Chang Liu, Zichen Zhang, Yongjiu Lv, Xiaochun Dong, Haisheng He, Jianping Qi, Yi Lu, Defang Ouyang*, Weili Zhao*, Wei Wu*. Near-infrared Fluorophores with Absolute Aggregation-caused Quenching and Negligible Fluorescence Re-illumination for In vivo Bioimaging of Nanocarriers. Aggregate 2023,4(2):e277

3. Ni Dong, Zhenyun Liu, Haisheng He, Yi Lu, Jianping Qi, Wei Wu*. “Hook&Loop” multivalent interactions based on disk-shaped nanoparticles strengthen active targeting. J Control Release 2023, 354: 279-293.

4. Haisheng He, Chang Liu, Yongjiu Lv, Jianping Qi, Yi Lu, Xiaochun Dong, Weili Zhao*, Wei Wu*. Accurate and Sensitive probing of micellization based on absolute aggregation-caused quenching effect. Aggregate 2022, 3(5):e163.

5. Wei Wu*, Tonglei Li*. Deepening the understanding of the in vivo and cellular fate of nanocarriers. Adv Drug Deliv Rev 2022, 189:114529.

6. Yifan Cai, Jianping Qi, Yi Lu, Haisheng He*, Wei Wu*. The in vivo fate of polymeric micelles. Adv Drug Deliv Rev 2022, 188: 114463.

7. Wufa Fan, Haixia Peng, Zhou Yu, Luting Wang, Haisheng He, Yuhua Ma, Jianping Qi, Yi Lu, Wei Wu*. The long-circulating effect of pegylated nanoparticles revisited via simultaneous monitoring of both the drug payloads and nanocarriers. Acta Pharm Sin B 2022, 12(5): 2479-2493.

8. Zichen Zhang, Jianping Qi, Yi Lu, Wei Wu*. An update on Oral Drug Delivery via Intestinal Lymphatic Transport. Acta Pharm Sin B 2021, 11(8): 2450-2469.

9. Zichen Zhang, Jianping Qi, Yi Lu, Wei Wu*, Hailong Yuan*. Peroral targeting of drug nanocarriers to sites beyond the gastrointestinal tract. Med Res Rev 2021, 41: 2590-2598.

10. Yinqian Yang, Yongjiu Lv, Chengying Shen, Tingting Shi, Haisheng He, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu*. In vivo dissolution of poorly water-soluble drugs: proof of concept based on fluorescence bioimaging. Acta Pharm Sin B 2021, 11: 1056-1068.

11. Haisheng He, Luting Wang, Yuhua Ma, Yinqian Yang, Yongjiu Lv, Zichen Zhang, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu, Wei Wu*. The biological fate of orally administered mPEG-PDLLA polymeric micelles. J Control Release 2020, 327: 725-736.

12. Zhou Yu, Wufa Fan, Luting Wang, Jianping Qi, Yi Lu, Wei Wu*. Effect of surface charges on oral absorption of intact solid lipid nanoparticles. Mol Pharm 2019, 16: 5013-5024.

13. Wei Wu*, Tonglei Li*. Unraveling the in vivo fate and cellular pharmacokinetics of drug nanocarriers. Adv Drug Deliv Rev 2019, 143: 1-2.

14. Jianping Qi, Xiongwei Hu, Xiaochun Dong, Yi Lu, Weili Zhao, Wei Wu*. Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool. Adv Drug Deliv Rev 2019, 143: 206-225.

15. Haisheng He, Yi Lu, Jianping Qi, Quangang Zhu, Zhongjian Chen*, Wei Wu*. Adapting liposomes for oral drug delivery. Acta Pharm Sin B 2019, 9(1): 36-48.

16. Haisheng He, Sifan Jiang, Yunchang Xie, Yi Lu, Jianping Qi, Xiaochun Dong, Weili Zhao, Zongning Yin, Wei Wu*. Reassessment of long circulation via monitoring of integral polymeric nanoparticles justifies a more accurate understanding. Nanoscale Horizons 2018, 3: 397-407

17. Jianping Qi, Jie Zhuang, Yongjiu Lv, Yi Lu, Wei Wu*. Exploiting or overcoming the dome trap for enhanced oral immunization and drug delivery. J Control Release 2018, 275:92-106.

18. Haisheng He, Yi Lu, Jianping Qi, Weili Zhao, Xiaochun Dong, Wei Wu*. Biomimetic thiamine- and niacin-decorated liposomes for enhanced oral delivery of insulin. Acta Pharm Sin B 2018, 8(1): 97-105.

19. Yuhua Ma, Haisheng He, Fei Xia, Yingxia Li, Yan Lu, Daofeng Chen, Jianping Qi, Wei Zhang*, Yi Lu*, Wei Wu*. In vivo fate of lipid-silybin conjugate nanoparticles: implications on enhanced oral bioavailability. Nanomedicine: Nanotechnology, Biology and Medicine 2017, 13(8): 2643-2654.

20. Fei Xia, Wufa Fan, Sifan Jiang, Yuhua Ma, Yi Lu, Jianping Qi, Ejaj Ahmad, Xiaochun Dong, Weili Zhao*, Wei Wu*. Size-Dependent Translocation of Nanoemulsions via Oral Delivery. ACS Applied Materials & Interfaces 2017, 9(26):21660-21672.

21. Ejaj Ahmad, Yunhai Feng, Jianping Qi, Wufa Fan, Yuhua Ma, Haisheng He, Fei Xia, Xiaochun Dong, Weili Zhao, Yi Lu*, Wei Wu*. Evidence of nose-to-brain delivery of nanoemulsions: cargoes but not vehicles. Nanoscale 2017, 9(3): 1174-1183.

22. Haisheng He, Jian Zhang, Yunchang Xie, Yi Lu, Jianping Qi, Ejaj Ahmad, Xiaochun Dong, Weili Zhao*, Wei Wu*. Bioimaging of Intravenous Polymeric Micelles Based on Discrimination of Integral Particles Using an Environment-Responsive Probe. Mol Pharm 2016, 13(11): 4013-9.

23. Zhiqiang Tian, Qin Yu, Yunchang Xie, Li Xiang, Fengqian Li, Yi Lu, Xiaochun Dong, Weili Zhao, Jianping Qi*, Wei Wu*. Controlling release of integral lipid nanoparticles based on osmotic pump technology. Pharm Res 2016, 33(8): 1988-97.

24. Yunchang Xie, Sifan Jiang, Fei Xia, Xiongwei Hu, Haisheng He, Zongning Yin, Jianping Qi, Yi Lu, Wei Wu*. Glucan microparticles thickened with thermosensitive gels as potential carriers for oral delivery of insulin. J Mater Chem B 2016, 4: 4040-4048.

25. Yunchang Xie, Xiongwei Hu, Haisheng He, Fei Xia, Yuhua Ma, Jianping Qi, Xiaochun Dong, Weili Zhao, Yi Lu*, Wei Wu*. Tracking Translocation of Glucan Microparticles Targeting M Cells: Implications for Oral Drug Delivery. J Mater Chem B 2016, 4: 2864-2873.

26. Jian Chen, Fei Xia, Sifan Jiang, Yunchang Xie, Zhang Bei, Yi Lu, Wei Wu*. Transmembrane Delivery of Anticancer Drugs through Self-assembly of Cyclic Peptide Nanotubes. Nanoscale 2016, 8: 7127-7136.

27. Xiongwei Hu, Wufa Fan, Zhou Yu, Yi Lu, Jianping Qi, Jian Zhang, Xiaochun Dong, Weili Zhao*, Wei Wu*. Evidence does not support intact absorption of solid lipid nanoparticles via oral delivery. Nanoscale 2016, 8: 7024-7035.

28. Yi Lu, Ye Li, Wei Wu*. Injected Nanocrystals for Targeted Drug Delivery. Acta Pharm Sin B 2016, 6(2): 106-113.

29. Xiongwei Hu, Jian Zhang, Zhou Yu, Yunchang Xie, Haisheng He, Jianping Qi, Weili Zhao*, Wei Wu*. Environment-responsive Aza-BODIPY Dyes Quenching in Water as Potential Probes to Visualize the in Vivo Fate of Lipid-based Nanocarriers. Nanomedicine: Nanotechnology, Biology, and Medicine 2015, 11(8): 1939-1948.

30. Mengmeng Niu, Ya’nan Tan, Peipei Guan, Lars Hovgaard, Yi Lu, Jianping Qi, Ruyue Lian, Xiaoyang Li, Wei Wu*. Enhanced oral absorption of insulin-loaded liposomes containing bile salts: a mechanistic study. Int J Pharm 2014, 460: 119-130.

31. Xingwang Zhang, Jianping Qi, Yi Lu, Xiaoyang Li, Wei He, Wei Wu*. Biotinylated liposomes as potential carriers for oral delivery of insulin. Nanomedicine: Nanotech Biol Med 2014, 10: 167-176.

32. Mengmeng Niu, Yi Lu, Lars Hovgaard, Peipei Guan, Yanan Tan, Ruyue Lian, Jianping Qi, Wei Wu*. Hypoglycemic activity and oral bioavailability of insulin-loaded liposomes containing bile salts in rats: the effect of cholate type, particle size and administered dose. Eur J Pharm Biopharm 2012 81(2):265-72

33. Huifang Liu, Jian Chen, Qing Shen, Wei Fu*, Wei Wu*. Molecular insights on the cyclic peptide nanotube-mediated transportation of anti-tumor drug 5-fluorouracil. Mol Pharm 2010, 7(6): 1985-1994.

34. Yaping Chen, Yi Lu, Jianming Chen, Jie Lai, Jing Sun, Fuqiang Hu, Wei Wu*. Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt. Int J Pharm, 2009,376: 153-160.

35. Cheng Lu, Yi Lu*, Jian Chen, Wentong Zhang, Wei Wu*. Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system. Eur J Pharm Biopharm 2007,66:210-219.

36. Xiuli Wei, Ningyun Sun, Baojian Wu, Chunhua Yin, Wei Wu*. Sigmoidal release of indomethacin from pectin matrix tablets: Effect of in situ crosslinking by calcium cations. Int J Pharm 2006,318:132-138.

37. Wei Wu*, Yang Wang, Li Que. Enhanced bioavailability of silymarin by self-microemulsifying drug delivery system. Eur J Pharm Biopharm 2006,63(3):288-294.